CRISPR
Why do CRISPR/Cas9 gene editing therapies fail after showing efficacy in rodent models
CRISPR/Cas9 gene editing therapies often show promising results in rodent models but can encounter several challenges when translated to human clinical settings, leading to failures or reduced efficacy. These challenges include differences in biology between species, immune responses, off-target effects, and delivery mechanisms. Differences in Biology Between Species Rodent models, such as mice, are extensively […]
Intellectual property landscape around prime editing
Intellectual Property Landscape Around Prime Editing Prime editing, a revolutionary genome editing technology, has been at the forefront of significant intellectual property developments and patent disputes. This technology, which allows for precise DNA edits without the need for double-strand breaks, was developed by Dr. David Liu and his team at the Broad Institute and Harvard […]