Sign or Symptom – Talk Bio

FDA Approves Tonix’s Tonmya: First New Fibromyalgia Drug in Over 15 Years

5 days ago talkbio0Tagged Analgesics, Non-Narcotic, Approved, Chronic pain, Clinical Trials, cyclobenzaprine, Fibromyalgia, Hairy Cell Leukemia, Phase 3, sublingual tablets, Tonix, Tonmya, United States Food and Drug Administration

Tonmya; FDA approval; fibromyalgia; Tonix Pharmaceuticals; non-opioid analgesic; cyclobenzaprine HCl sublingual tablets; chronic pain; phase 3 clinical trials

Vertex Drops Next-Generation Pain Drug After Phase 2 Failure, Casts Doubt on Broader Journavx Expansion

3 weeks ago talkbio0Tagged Acute onset pain, Approved, Drug Development, Journavx, non-opioid pain drugs, Pain management, Peripheral neuropathic pain, Sodium Channel Blockers, United States Food and Drug Administration, VX-993

Vertex Pharmaceuticals; Journavx; VX-993; pain management; acute pain; phase 2 clinical trial; sodium channel inhibitor; non-opioid pain drugs; FDA approval; peripheral neuropathic pain; drug development

Praxis touts ‘best-in-disease’ epilepsy data, but shares dip

3 weeks ago talkbio0Tagged anti-seizure medication, Clinical Research, Clinical Trials, Epilepsy, focal onset seizures, Market, Praxis Precision Medicines, Radiant heater, Seizures, vormatrigine

Praxis Precision Medicines; epilepsy; vormatrigine; RADIANT study; focal onset seizures; Phase 2 trial; seizure reduction; clinical trial; anti-seizure medication; stock market

Bayer’s Lynkuet (elinzanetant) Wins First-in-World Approval in UK, Challenging Astellas’ Hot Flash Drug

1 month ago talkbio0Tagged Approved, Astellas, Bayer, Elinzanetant, Hot flushes, Lynkuet, Menopause, MHRA, non-hormonal therapy, UK, vasomotor symptom

Bayer; elinzanetant; Lynkuet; menopause; hot flashes; vasomotor symptoms; Astellas; non-hormonal therapy; MHRA approval; UK first approval

Leap Therapeutics Slashes 75% of Workforce, Ends Clinical Trial, Considers Strategic Options

2 months ago talkbio0Tagged Biotech Layoffs, Clinical Trials, FL-501, Flatulence, LEAP, Sirexatamab, strategic alternatives

Leap Therapeutics; workforce reduction; biotech layoffs; clinical trial; strategic alternatives; sirexatamab; FL-501; R&D wind down

Amgen Adjusts Phase 3 Dosing for MariTide After Midstage Side Effects Concerns

2 months ago talkbio0Tagged Adverse event, amgen, Clinical Trials, Dosage, Escalation, gastric inhibitory polypeptide receptor, GLP-1 receptor, MariTide, Obesity, Phase 3, Vomiting

Amgen; MariTide; Phase 3; obesity treatment; dose escalation; vomiting; adverse events; clinical trial; GLP-1 receptor; GIP receptor

Eli Lilly Acquires SiteOne for Up to $1B to Expand Non-Opioid Pain Pipeline

3 months ago talkbio0Tagged Acquisition, Chronic pain, Drug Industry, eli lilly, Nav1.8 inhibitor, neuroscience pipeline, non-opioid pain treatment, SiteOne Therapeutics, STC-004

Eli Lilly; SiteOne Therapeutics; non-opioid pain treatment; STC-004; acquisition; Nav1.8 inhibitor; chronic pain; neuroscience pipeline; Vertex; pharmaceutical industry

Eroding Immunity: Vaccine Hesitancy and Cynicism With Paul Offit

4 months ago talkbio0Tagged cynicism, Immune response, mandates, Misinformation, Offit, Paul Offit, Urinary hesitation, Vaccines

Vaccines, Urinary hesitation, Offit, cynicism, Misinformation, Immune response, Paul Offit, mandates

Octagon Therapeutics Ceases Operations Due to R&D Challenges and Unresolved Biology Questions

4 months ago talkbio0Tagged Autoimmune Diseases, B cell immunomodulator program, biology (field), Flatulence, Nordisk alliance, OCT50, Programs - Publication Format

Autoimmune disease biotech, B cell immunomodulator program, OCT50 program, Novo Nordisk alliance, Winding down operations, Unresolved biology challenges

Steminent Stands Ready to Showcase Novel MSC-based Therapy for Spinocerebellar Ataxia at Global Stage

4 months ago talkbio0Tagged Ataxia, Ataxia, Spinocerebellar, Machado-Joseph Disease, Mesenchymal Stem Cells, Spinocerebellar, Stemchymal

Ataxia, Spinocerebellar, Stemchymal, Machado-Joseph Disease, Spinocerebellar, Ataxia, Mesenchymal Stem Cells