Research Activity – Page 2

Patient Dies from Thrombotic Stroke in Pfizer’s Hympavzi Hemophilia Trial After Minor Surgery

1 month ago talkbio0Tagged Clinical Trials, Hemophilia A, HYMPAVZI, marstacimab, Patient Death, Pfizer, Thrombotic Stroke

Pfizer; Hympavzi; marstacimab; hemophilia; thrombotic stroke; patient death; clinical trial

FDA places partial clinical hold on Merck and Daiichi Sankyo’s I-DXd lung cancer trial after interstitial lung disease deaths

1 month ago talkbio0Tagged Antibody-Drug Conjugates, Clinical Trials, Daiichi, Deruxtecan, grade 5 ILD, I-DXd, IDeate-Lung02, ifinatamab, Lung Diseases, Interstitial, Merck, Partial, Sankyo, Small cell carcinoma of lung, United States Food and Drug Administration

FDA partial clinical hold; ifinatamab deruxtecan; I-DXd; IDeate-Lung02; Merck; Daiichi Sankyo; small cell lung cancer; interstitial lung disease; grade 5 ILD; antibody-drug conjugate; clinical trial deaths

Moderna Lands CEPI as New Backer for Its Pandemic Flu (H5 Bird Flu) Program

1 month ago talkbio0Tagged CEPI, coalition, Epidemic Preparedness Innovations, Funding, H5 bird flu, Moderna, mRNA Vaccine, pandemic influenza, pandemic preparedness, Phase 3 trial, Vaccine Development

Moderna; CEPI; Coalition for Epidemic Preparedness Innovations; pandemic influenza; H5 bird flu; mRNA vaccine; Phase 3 trial; pandemic preparedness; vaccine development; funding

Quantori and Expert Systems Partner to Accelerate Drug Discovery with Foundational Predictive AI Models

1 month ago talkbio0Tagged AI models, Dosage Forms, Drug Discovery, Expert Systems, Q-Scientist, Quantori, R&D

Quantori; Expert Systems; drug discovery; AI models; Q-Scientist; pharmaceutical R&D

Ipsen’s Fidrisertib Fails Primary Endpoint in Pivotal Phase II FALKON Trial for Rare Bone Disease FOP

1 month ago talkbio0Tagged Clinical Trials, FALKON, Fibrodysplasia Ossificans Progressiva, fidrisertib, Heterotopic Ossification, Ipsen, Phase II Failure

Ipsen; fidrisertib; FALKON trial; FOP; Phase II failure; heterotopic ossification

Lilly seeks rapid FDA approval for oral GLP-1 orforglipron after positive obesity “switching” study

1 month ago talkbio0Tagged Approved, Clinical Trials, Eli, Glucagon-Like Peptide 1, injectable incretins, national priority review voucher, Obesity, Oral cavity, orforglipron, Phase 3 trial, United States Food and Drug Administration, Wegovy, weight maintenance, Zepbound

Eli Lilly; orforglipron; oral GLP-1; FDA approval; national priority review voucher; ATTAIN-MAINTAIN trial; obesity treatment; weight maintenance; Zepbound; Wegovy; injectable incretins; Phase 3 trial

Models are out, molecules are in as AI drug startups sprint to the clinic

1 month ago talkbio0Tagged Absci, AI drug discovery, AI-designed molecules, Clinical Trials, clinical-stage AI startups, Funding, Insilico Medicine, PsiThera, Recursion Pharmaceuticals, small molecule therapeutics

AI drug discovery; AI-designed molecules; clinical-stage AI startups; small-molecule therapeutics; biotech funding; Insilico Medicine; Recursion Pharmaceuticals; Absci; PsiThera; clinical trials

Harbour BioMed inks $90M upfront, $1B+ antibody alliance with Bristol Myers Squibb

1 month ago talkbio0Tagged biobucks, Burning Mouth Syndrome, China, Clinical Trials, global strategic collaboration, Harbour BioMed, Harbour Mice ® technology, Immunology, License Agreement, milestones, multi-specific antibodies, Myers Squibb, Neoplasms

Harbour BioMed; Bristol Myers Squibb; BMS; multi-specific antibodies; $90 million upfront; $1.035 billion milestones; global strategic collaboration; license agreement; Harbour Mice technology; immunology; oncology; biobucks deal; China early clinical trials

China’s fast, low-cost gene and cell therapy testing boom draws Western interest

1 month ago talkbio0Tagged Advanced Therapy Medicinal Products, ATMP regulation China, CDE, Cell Therapy, China, clinical trial review, Clinical Trials, gene therapy, N-methyl-N-2-(methylsulfinyl)ethylpropionic acid amide, reforms, Shortened, therapies testing, Western biotech

China clinical trials; gene therapy; cell therapy; advanced therapy medicinal products; ATMP regulation China 2025; shortened clinical trial review; cheap clinical trials; Western biotech in China; NMPA CDE reforms; novel therapies testing

Pilatus Raises $14M for First-in-Human Study of Anti-CD36 mAb

1 month ago talkbio0Tagged Anti-CD36 mAb, First-in-Human Study, Funding, Pilatus

Pilatus; funding; anti-CD36 mAb; first-in-human study; biotech