Molecular Biology Research Technique – Page 4

CRISPR Gene Editing Therapy Can Be Administered Twice, Intellia Study Suggests

10 months ago talkbio0Tagged Amyloidosis, Clustered Regularly Interspaced Short Palindromic Repeats, Gene Modification, gene therapy, Intellia, Prealbumin, re-dosing

CRISPR, gene editing, Intellia Therapeutics, transthyretin amyloidosis, gene therapy, re-dosing

Exsilio Therapeutics Launches with $82 Million to Develop mRNA-Based Genomic Medicines Under Tal Zaks’ Leadership

10 months ago talkbio0Tagged Approved, Exsilio, Gene Modification, gene therapy, genomic medicines, Lipids, nanoparticle delivery, RNA, Messenger, safety profile, Tal Zaks

Exsilio Therapeutics, mRNA, genomic medicines, Tal Zaks, gene therapy, gene editing, lipid nanoparticle delivery, redosing, safety profile, gene therapy approval

Intellia Therapeutics Advances in Hereditary Angioedema Treatment with Durable One-Dose CRISPR Gene Editing Therapy

11 months ago talkbio0Tagged Angioedemas, Hereditary, Clinical Trials, Clustered Regularly Interspaced Short Palindromic Repeats, Gene Modification, Intellia, Long-term, single-dose

Intellia Therapeutics, Hereditary Angioedema (HAE), CRISPR Gene Editing, NTLA-2002, Single-Dose Treatment, Long-Term Data, Clinical Trials

Intellia Therapeutics Reports Promising Long-Term Data for Single-Dose HAE Therapy

11 months ago talkbio0Tagged Angioedemas, Hereditary, Clustered Regularly Interspaced Short Palindromic Repeats, Gene Modification, Intellia, Long-term, NTLA-2002, single-dose

Intellia Therapeutics, NTLA-2002, Hereditary Angioedema (HAE), CRISPR Gene Editing, Single-Dose Treatment, Long-Term Data

Early Detection and Personalized Treatment of Colorectal Cancer: The Promise of Whole Genome Sequencing-Based Circulating Tumor DNA Tracking” ###

11 months ago talkbio0Tagged Adjuvant Therapy, Circulating, Circulating Tumor DNA, Colorectal Carcinoma, Detection, Liquid Biopsy, Molecular residual disease, MRD, Personalized Treatment, Whole Genome Sequencing

Circulating tumor DNA (ctDNA), Whole genome sequencing (WGS), Colorectal cancer, Early detection, Personalized treatment, Adjuvant therapy, Molecular residual disease (MRD), Liquid biopsies

Revolutionizing Biotherapeutic Analysis: Novel icIEF Fractionation and Mass Spectrometry for Charge Characterization

11 months ago talkbio0Tagged analytical techniques, Biological Factors, biotherapeutics, Characterization, charge amounts, Chemical fractionation, Imaged Capillary Isoelectric Focusing, Protein Analysis, protein charge, Protein Purification, protein separation, therapeutic protein, Variant

biotherapeutics, icIEF fractionation, mass spectrometry, charge characterization, protein analysis, therapeutic proteins, biopharmaceuticals, analytical techniques, protein purification, protein separation, protein charge variants.

Revolutionizing Protein Design: Nabla Bio Secures $26M for AI-Driven Pharmaceutical Solutions

11 months ago talkbio0Tagged Artificial Intelligence, Biotechnology, Drug Discovery, genAI protein design, healthcare innovation, Nabla Bio, pharmaceutical partners, Protein Engineering

Nabla Bio, genAI protein design, funding, pharmaceutical partners, biotechnology, protein engineering, drug discovery, artificial intelligence, healthcare innovation.

Preliminary CRISPR-Based HIV Treatment Study Shows Limited Success

12 months ago talkbio0Tagged Clustered Regularly Interspaced Short Palindromic Repeats, curative potential, Gene Modification, HIV, Success

CRISPR, HIV, gene editing, treatment, study, curative potential, early study, limited success

Revolutionary Gene Insertion Techniques Unveiled at #ASGCT24: A Glimpse into the Future of Genetic Engineering

12 months ago talkbio0Tagged ASGCT24, Closed Doors, gene insertion techniques, Genetic Engineering, Scientist, startups

Gene Insertion Techniques, #ASGCT24, Genetic Engineering, Scientists, Startups, Closed Doors

Molecular Biology Research Technique

Why do CRISPR/Cas9 gene editing therapies fail after showing efficacy in rodent models

12 months ago12 months ago talkbio0Tagged CRISPR

CRISPR/Cas9 gene editing therapies often show promising results in rodent models but can encounter several challenges when translated to human clinical settings, leading to failures or reduced efficacy. These challenges include differences in biology between species, immune responses, off-target effects, and delivery mechanisms. Differences in Biology Between Species Rodent models, such as mice, are extensively […]