Functional Concept – Page 8

KRAS G12C inhibitors, non-small cell lung cancer (NSCLC), targeted therapy, sotorasib (Lumakras), adagrasib (Krazati), biomarker testing, Revolution Medicines

FDA Delays Continue as Regulator Misses Review Date for GSKs Nucala

4 months ago talkbio0Tagged Chronic Obstructive Airway Disease, delays, GSK 's, Nucala, PDUFA, Target, United States Food and Drug Administration

United States Food and Drug Administration, Nucala, Chronic Obstructive Airway Disease, GSK ‘s, Target, delays, PDUFA

Citing tariffs, Illumina slashes guidance, confirms SEC’s Grail investigation is closed

4 months ago talkbio0Tagged Acquisition (action), Divestiture, Evaluation, Grail, Illumina, SEC

Illumina, SEC, Acquisition (action), Evaluation, divestiture, Grail

FDA eyes full AI integration by June as Makary touts genAI pilot success

4 months ago talkbio0Tagged Aortic Valve Insufficiency, Artificial Intelligence, DNA Integration, June, Makary, United States Food and Drug Administration

United States Food and Drug Administration, Aortic Valve Insufficiency, DNA Integration, Artificial Intelligence, Makary, June

In first oncology expert meeting under Makary, FDA spotlights cancer drugs from J&J, Pfizer, Roche and UroGen

4 months ago talkbio0Tagged J&J, oncology expert, Pfizer, Roche (company), United States Food and Drug Administration, UroGen

United States Food and Drug Administration, oncology expert, J&J, Pfizer, Roche (company), UroGen

Marea Therapeutics Reports Positive Phase 2a Results for MAR001 in Lowering Remnant Cholesterol and Triglycerides

4 months ago4 months ago talkbio0Tagged Adverse event, ANGPTL4 gene, Antibodies, Dosage, Embryonic remnant, Hypertriglyceridemia, MAR001, MAR001[1, Phase 2a clinical trial, placebo-adjusted mean reduction, Positive

MAR001, Antibodies, ANGPTL4 gene, Embryonic remnant, Hypertriglyceridemia, Phase 2a clinical trial, Positive, placebo-adjusted mean reduction, Dosage, Adverse event, MAR001[1

CRISPR Therapeutics’ gene editing therapy reduces bad cholesterol and triglycerides by as much as 80%

4 months ago talkbio0Tagged cholesterol, Clinical Trials, Clustered Regularly Interspaced Short Palindromic Repeats, CTX310, Gene Modification, Genes, In Vivo, LDL Cholesterol Lipoproteins, Triglycerides

Gene Modification, Clustered Regularly Interspaced Short Palindromic Repeats, Triglycerides, LDL Cholesterol Lipoproteins, In Vivo, CTX310, Clinical Trials, cholesterol, Genes