AI Advances in High-Throughput Genomics: Sequence-Based Screening and Rapid Genome Analysis
Breakthrough Genomics unveiled Virtual Geneticist® AI platform at ASHG 2025, enabling whole exome and whole genome sequencing interpretation in minutes instead of hours via LLM-powered literature curation and ACMG classification.1
Roche and Boston Children’s Hospital achieved the fastest human genome sequencing and analysis record under 4 hours using Sequencing by Expansion (SBX), expanding DNA into Xpandomers for improved accuracy and speed.2
Agentic AI platforms in 2026, like those in Variant Bio and Boehringer Ingelheim partnerships, automate experiment design and refinement, accelerating drug discovery for potential high-throughput screening of candidates.3
No direct reports found on sequence-based AI screening billions of small molecule or antibody candidates in hours; closest advancements focus on genomic interpretation speed rather than molecular candidate screening.12
Sources:
1. https://www.morningstar.com/news/pr-newswire/20251021sf01620/breakthrough-genomics-showcases-largest-interpreted-literature-database-and-unveils-new-ai-capabilities-at-ashg-2025
2. https://www.scientificdiscovery.dev/p/medical-breakthroughs-in-2025