Ipsen to Acquire ImCheck Therapeutics for €350 Million to Expand Immunotherapy Pipeline
Ipsen has entered a definitive agreement to acquire ImCheck Therapeutics, a private French biotechnology company specializing in next-generation immuno-oncology therapies13911.
ImCheck’s shareholders will receive an upfront payment of €350 million, with total transaction value potentially reaching up to €1 billion, contingent on regulatory and sales-based milestones135911.
ImCheck is known for its work on the butyrophilin superfamily—a novel group of immune-regulatory proteins—with its lead candidate ICT01, a first-in-class monoclonal antibody targeting BTN3A137.
ICT01 is currently in Phase I/II clinical trials for acute myeloid leukemia (AML) in patients unfit for intensive chemotherapy, addressing a significant unmet medical need137.
ICT01 received Orphan Drug Designations from both the U.S. FDA and the European Medicines Agency in July 20253.
The acquisition strengthens Ipsen’s oncology pipeline, expanding its leadership in the immunotherapy space and leveraging ImCheck’s novel approach to cancer treatment2348.
Sources:
1. https://eqtgroup.com/news/eqt-life-sciences-imcheck-therapeutics-to-be-acquired-by-ipsen-in-a-transaction-valued-at-up-to-eur-1-billion-2025-10-22
2. https://www.ipsen.com/press-release/
3. https://www.imchecktherapeutics.com/all-press-release/news/ipsen-to-acquire-imcheck-therapeutics-expanding-its-leadership-in-oncology-strengthening-its-pipeline/
5. https://www.europeanpharmaceuticalreview.com/news/267297/ipsen-strikes-e1bn-deal-to-acquire-french-biotech-imcheck-therapeutics/
7. https://pharmaphorum.com/news/ipsen-buys-imcheck-adding-mid-stage-leukaemia-drug
8. https://www.ipsen.com/press-releases/ipsen-delivers-strong-sales-in-the-first-nine-months-of-2025-and-further-upgrades-its-full-year-guidance-3170798/
9. https://www.globenewswire.com/news-release/2025/10/22/3170788/0/en/Ipsen-to-acquire-ImCheck-Therapeutics-expanding-its-leadership-in-oncology-strengthening-its-pipeline.html
11. https://www.pharmafocuseurope.com/news/ipsen-to-acquire-imcheck-therapeutics-expanding-its-leadership-in-oncology-and-strengthening-its-pipeline