Trump signs sweeping executive order to cut US drug prices by ‘up to 90%’

Title

Trump Signs Sweeping Executive Order to Slash U.S. Drug Prices by Up to 90%

Keywords

  • Trump executive order
  • U.S. drug prices
  • prescription drug costs
  • most favored nation pricing
  • pharmaceutical industry
  • Medicare and Medicaid
  • Health and Human Services (HHS)
  • pharmaceutical price negotiation
  • medication imports
  • drug price reduction policy

Key Facts

  • President Donald Trump signed a sweeping executive order on May 12, 2025, aiming to reduce U.S. prescription drug prices by up to 90%3.
  • The order implements a "most favored nation" (MFN) policy, requiring drug prices paid by the U.S. government to match the lowest prices paid by any economically advanced country3.
  • Drugmakers have a 30-day deadline to negotiate new, lower prices with the Department of Health and Human Services (HHS); if negotiations fail, the government will implement limits tying U.S. drug costs to international benchmarks23.
  • If drugmakers do not comply, the HHS has the authority to enforce target prices or initiate rulemaking to impose MFN pricing13.
  • The new policy covers Medicare and Medicaid, which together insure nearly 150 million Americans, though its immediate effect on the privately insured remains unclear23.
  • The pharmaceutical industry strongly opposes the order, warning it could cost them up to $1 trillion over a decade and potentially hinder research and development of new drugs12.
  • Previous iterations of similar policies have faced legal challenges from pharmaceutical companies, and experts expect significant resistance and potential litigation to this new executive order13.
  • The order also hints at expanding medication imports beyond Canada and considers export restrictions as further means to control drug costs1.
  • The executive order's details and implementation timeline remain vague, leaving its ultimate impact subject to further regulatory action and likely court battles3.

Sources:

1. https://www.ajmc.com/view/trump-executive-order-could-reduce-pharmaceutical-costs-by-59-

2. https://www.latimes.com/science/story/2025-05-12/trump-executive-order-30-day-deadline-for-drugmakers-to-lower-prices

3. https://www.fiercepharma.com/pharma/trump-signs-sweeping-executive-order-cut-price-drugs-us-90

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