Truveta Genome Project: A Historic 10M Genome Sequencing Initiative Backed by Regeneron, Illumina, and Leading Health Systems
Project Scope:
The Truveta Genome Project aims to create the largest and most diverse database of genotypic and phenotypic information by sequencing the exomes of tens of millions of consented and de-identified volunteers15.
Partnership:
Regeneron and Illumina are collaborating with Truveta and leading American health systems to extend the Regeneron Genetics Center's DNA sequence-linked healthcare database through genetic sequencing of up to ten million additional patient volunteers34.
Investment:
Regeneron is investing $119.5 million in Truveta's Series C Financing Round to support the project3.
Data Utilization:
The project will link genetic data to de-identified medical records, enabling researchers to transform healthcare by accelerating drug discovery, optimizing clinical trials, and improving disease prevention and diagnosis13.
AI Integration:
Truveta AI will play a crucial role in making genomic and omics data useful for research by tackling challenges related to scale and semantics5.
Diversity and Impact:
The project aims to represent the full diversity of the US across ancestries, ethnicities, genders, and other social drivers of health, with the goal of improving healthcare equity and advancing scientific innovation13.
Sources:
1. https://www.truveta.com/truveta-genome-project/
3. https://www.globenewswire.com/news-release/2025/01/13/3008227/0/en/Regeneron-Collaborates-with-Truveta-and-Leading-American-Health-Systems-to-Massively-Extend-its-DNA-Sequence-Linked-Healthcare-Database-to-Further-Advance-Scientific-Innovation-and.html
4. https://sdbn.org/san-diego-biotech-news/2025/01/13/stat-truveta-enlists-health-systems-drugmakers-to-launch-ambitious-new-genomic-database/
5. https://www.truveta.com/blog/news/saving-lives-with-genetic-data/