From Partnership to Acquisition: The $1.5 Billion Journey of Roche and Poseida Therapeutics

Acquisition Agreement:
Poseida Therapeutics, Inc. has entered into a merger agreement to be acquired by Roche Holdings, Inc. for a total equity value of approximately $1.5 billion24.

Transaction Terms:
The acquisition price is $9.00 per share in cash at closing, plus a non-tradeable contingent value right (CVR) to receive up to an aggregate of $4.00 per share in cash upon achievement of specific milestones24.

Background:
The acquisition traces back to August 2022 when Roche and Poseida formed a strategic partnership, with Roche paying $110 million upfront13.

Strategic Impact:
The acquisition will establish a new core capability for Roche in allogeneic cell therapy, focusing on CAR-T programs for hematologic malignancies, solid tumors, and autoimmune diseases25.

Poseida's Technology:
Poseida has pioneered a proprietary non-viral technology platform to design, develop, and manufacture allogeneic T stem cell memory cells (T SCM)-rich CAR-T therapies, which are considered ideal for CAR-T therapy due to their long-lived, multi-potent, and self-replicating nature25.

Closing Expectations:
The transaction is expected to close in the first quarter of 2025, subject to customary closing conditions, including regulatory review and the tender of a majority of Poseida's outstanding shares24.

Sources:

1. https://bcbn.org/boston-cambridge-biotech-news/2024/12/10/roche-said-it-didnt-want-to-buy-poseida-last-year-a-look-at-how-the-1-5b-buyout-came-to-be/

2. https://www.prnewswire.com/news-releases/poseida-therapeutics-inc-announces-agreement-to-be-acquired-by-roche-holdings-inc-302316189.html

3. https://www.cafepharma.com/content/roche-said-it-didn%E2%80%99t-want-buy-poseida-last-year-look-how-15b-buyout-came-be

4. https://investors.poseida.com/news-releases/news-release-details/poseida-therapeutics-inc-announces-agreement-be-acquired-roche

5. https://www.biopharma-reporter.com/Article/2024/11/28/roche-acquires-car-t-developer-poseida-therapeutics/

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