Nuvig Therapeutics Secures $161M Funding for Phase 2 Study in Autoimmune Diseases
Funding:
Nuvig Therapeutics has raised $161 million to support its Phase 2 study for treating autoimmune diseases3.
Lead Molecule:
The company's lead molecule, NVG-2089, is a manufactured antibody fragment that mimics the action of intravenous immunoglobulin (IVIg) but with improved efficacy and reduced dosing requirements12.
Disease Focus:
NVG-2089 is initially being tested for Chronic Idiopathic Demyelinating Polyneuropathy (CIDP), a condition that leads to gradual loss of walking ability and numbness in extremities2.
Synthetic Manufacturing:
Nuvig's use of synthetic manufacturing eliminates the need for costly blood donations, addressing supply shortages and rationing issues associated with IVIg1.
Future Plans:
The company plans to test NVG-2089 in one or two different dermatological autoimmune disorders where IVIG use is validated2.
Mission:
Nuvig Therapeutics aims to bring innovative and transformational therapies to patients with chronic autoimmune diseases by inducing mechanisms that restore immune homeostasis45.
Sources:
1. https://www.nvp.com/blog/nuvig-pioneers-treatment-neuro-inflammatory-disorders/
2. https://www.biocom.org/lifelines/interviews/member-spotlight-nuvig-therapeutics/
3. https://medcitynews.com/2024/05/lycia-therapeutics-lands-106m-for-protein-degraders-that-treat-autoimmune-inflammatory-diseases/
4. https://www.nuvigtherapeutics.com
5. https://www.nuvigtherapeutics.com/nuvig-launches-to-develop-novel-immune-therapeutics-for-chronic-inflammatory-and-autoimmune-diseases/