TriNetX Achieves Record as the Most Cited Real-World Electronic Health Record Dataset in Peer-Reviewed Research
As of August 2025, TriNetX has surpassed 2,000 citations in peer-reviewed publications, making it the most cited electronic health record (EHR) dataset worldwide17.
TriNetX's year-over-year citation growth is approaching 80%, with annual citations rising from 96 in 2021 to 952 in just the first eight months of 20251.
TriNetX is cited nearly 1,300% more often than its closest competitor (149 citations), indicating its dominance in real-world data for health research17.
The platform is used extensively by clinical researchers, public health agencies, and healthcare organizations globally for research published in leading journals like Nature Medicine, The Journal of Allergy and Clinical Immunology, and JAMIA Open1.
Significant recent network expansions have occurred, with user growth particularly strong in Latin America (70% increase) and Asia Pacific (31% increase) between September 2024 and September 20251.
TriNetX supports advanced cohort design, outcomes analysis, and statistical methods (such as propensity score matching) while allowing real-time querying and outcome tracking across an estimated 179 million patient records as of April 20255.
Recent TriNetX analytics and reports have highlighted the platform's impact on rare disease innovation and on accelerating clinical trials through real-world data partnerships, notably including a joint venture with Fujitsu to expand access in Japan23.
A notable recent organizational update is the planned departure of TriNetX’s founding CEO, Gadi Lachman, who will transition to a board role after 11 years in operational leadership3.
TriNetX has received recognition as one of the top healthcare software companies of 2025 and continues to drive the adoption of artificial intelligence and real-world data in pharmaceutical research34.
Sources:
1. https://www.prnewswire.com/in/news-releases/trinetx-becomes-the-most-cited-real-world-data-source-in-peer-reviewed-research-302583829.html
2. https://trinetx.com/press-releases/new-trinetx-research-impact-report-illuminates-how-real-world-data-is-fueling-rare-disease-innovation/
3. https://trinetx.com/real-world-resources/press-releases/
4. https://trinetx.com/press-releases/new-trinetx-survey-reveals-biopharmas-bold-embrace-of-real-world-data-and-artificial-intelligence-but-warns-of-looming-barriers/
5. https://mail.biochemia-medica.com/en/journal/35/3/10.11613/BM.2025.030502/fullArticle
7. https://trinetx.com/blog/proof-in-publications-the-most-cited-the-most-trusted-trinetx-real-world-data/