Nura Bio, a clinical-stage biopharmaceutical company developing neuroprotective small‑molecule therapies, has completed a $73.8 million Series B financing round to advance its SARM1 inhibitor pipeline for neurodegenerative diseases. Proceeds will fund clinical proof‑of‑biology studies for the two lead candidates, NB‑4746 and NB‑9402, including the Phase Ib/IIa study of NB‑4746 in amyotrophic lateral sclerosis (ALS) and the first‑in‑human Phase Ia trial of NB‑9402 in healthy volunteers. SARM1 is a neuronally enriched NAD hydrolase that acts as a central driver of axon degeneration; inhibiting it is intended to block the axon‑intrinsic metabolic cascade that leads to nerve‑fiber loss, with potential across ALS, peripheral neuropathy, and ocular neurological diseases. Sources: Nura Bio Raises $73.8M Series B for ALS SARM1 - AllSci Nura Bio raises $140 million in series A extension Nura Bio discovers new SARM1 inhibitors for neurodegeneration News & Literature | Nura Bio™...
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